Comparing FibroGen (NASDAQ:FGEN) and Neoleukin Therapeutics (NASDAQ:NLTX)

FibroGen (NASDAQ:FGEN) and Neoleukin Therapeutics (NASDAQ:NLTX) are both medical companies, but which is the superior stock? We will compare the two companies based on the strength of their dividends, valuation, analyst recommendations, risk, institutional ownership, earnings and profitability.

Valuation and Earnings

This table compares FibroGen and Neoleukin Therapeutics’ revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
FibroGen $212.96 million 18.67 -$86.42 million ($1.03) -44.25
Neoleukin Therapeutics $25.00 million 21.51 -$31.58 million ($1.34) -8.25

Neoleukin Therapeutics has lower revenue, but higher earnings than FibroGen. FibroGen is trading at a lower price-to-earnings ratio than Neoleukin Therapeutics, indicating that it is currently the more affordable of the two stocks.

Analyst Ratings

This is a breakdown of current ratings and recommmendations for FibroGen and Neoleukin Therapeutics, as reported by

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
FibroGen 0 2 2 0 2.50
Neoleukin Therapeutics 0 0 1 0 3.00

FibroGen presently has a consensus price target of $52.33, suggesting a potential upside of 14.82%. Neoleukin Therapeutics has a consensus price target of $20.00, suggesting a potential upside of 80.83%. Given Neoleukin Therapeutics’ stronger consensus rating and higher probable upside, analysts clearly believe Neoleukin Therapeutics is more favorable than FibroGen.

Volatility and Risk

FibroGen has a beta of 1.95, indicating that its stock price is 95% more volatile than the S&P 500. Comparatively, Neoleukin Therapeutics has a beta of -6.92, indicating that its stock price is 792% less volatile than the S&P 500.


This table compares FibroGen and Neoleukin Therapeutics’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
FibroGen 11.81% 7.33% 4.81%
Neoleukin Therapeutics N/A -26.13% -24.97%

Insider and Institutional Ownership

68.4% of FibroGen shares are owned by institutional investors. Comparatively, 38.8% of Neoleukin Therapeutics shares are owned by institutional investors. 7.8% of FibroGen shares are owned by company insiders. Comparatively, 4.0% of Neoleukin Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.


FibroGen beats Neoleukin Therapeutics on 10 of the 14 factors compared between the two stocks.

FibroGen Company Profile

FibroGen, Inc., a biopharmaceutical company, discovers, develops, and commercializes therapeutics to treat serious unmet medical needs. It is developing Roxadustat, an oral small molecule inhibitor of hypoxia inducible factor prolyl hydroxylases (HIF-PHs) that is in Phase III clinical development for the treatment of anemia in chronic kidney disease in the United States and Europe; and in Phase II/III development in China for anemia associated with myelodysplastic syndromes. The company is also developing Pamrevlumab, a human monoclonal antibody that inhibits the activity of connective tissue growth factor for the treatment of idiopathic pulmonary fibrosis, pancreatic cancer, liver fibrosis, and diabetic kidney disease, as well as Duchenne muscular dystrophy; and FG-5200, a corneal implant medical device for the treatment of corneal blindness resulting from partial thickness corneal damage. It has collaboration agreements with Astellas Pharma Inc. and AstraZeneca AB. The company was incorporated in 1993 and is headquartered in San Francisco, California.

Neoleukin Therapeutics Company Profile

Neoleukin Therapeutics, Inc., a biopharmaceutical company, develops immunotherapies using protein design technology. The company's lead product candidate is NL-201, a computationally-designed de novo protein therapeutic for the treatment of IL-2/IL-15 cancer immunotherapy. It also engages in research activities for the treatment of autoimmunity and allergy. The company was formerly known as Aquinox Pharmaceuticals, Inc. and changed its name to Neoleukin Therapeutics, Inc. in August 2019. Neoleukin Therapeutics, Inc. was founded in 2003 and is headquartered in Seattle, Washington.

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