Financial Contrast: Immune Therapeutics (OTCMKTS:IMUN) vs. Phio Pharmaceuticals (OTCMKTS:PHIO)

Immune Therapeutics (OTCMKTS:IMUN) and Phio Pharmaceuticals (NASDAQ:PHIO) are both small-cap medical companies, but which is the better business? We will compare the two companies based on the strength of their analyst recommendations, institutional ownership, profitability, valuation, risk, dividends and earnings.

Risk and Volatility

Immune Therapeutics has a beta of 2.09, indicating that its stock price is 109% more volatile than the S&P 500. Comparatively, Phio Pharmaceuticals has a beta of 1.45, indicating that its stock price is 45% more volatile than the S&P 500.

Valuation and Earnings

This table compares Immune Therapeutics and Phio Pharmaceuticals’ top-line revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Immune Therapeutics $110,000.00 0.03 -$8.18 million N/A N/A
Phio Pharmaceuticals $140,000.00 14.00 -$7.36 million ($57.14) -0.05

Phio Pharmaceuticals has higher revenue and earnings than Immune Therapeutics.

Institutional and Insider Ownership

5.1% of Immune Therapeutics shares are owned by institutional investors. 11.7% of Immune Therapeutics shares are owned by company insiders. Comparatively, 2.1% of Phio Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.


This table compares Immune Therapeutics and Phio Pharmaceuticals’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Immune Therapeutics N/A N/A -6,367.12%
Phio Pharmaceuticals N/A -74.97% -62.32%

Analyst Recommendations

This is a breakdown of recent recommendations for Immune Therapeutics and Phio Pharmaceuticals, as reported by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Immune Therapeutics 0 0 0 0 N/A
Phio Pharmaceuticals 0 0 0 0 N/A

Immune Therapeutics Company Profile

Immune Therapeutics, Inc., together with its subsidiaries, focuses on the development and commercialization of therapeutic treatments for cancer, human immunodeficiency virus (HIV)/AIDS, and autoimmune and immune disorders in the United States and internationally. It develops methionine enkephalin IRT-101, a small synthetic pentapeptide; and low-dose naltrexone IRT-103, an opioid receptor antagonist that stimulates and/or regulates the immune system to treat a range of autoimmune diseases, including multiple sclerosis; immune disorders, such as Crohn's disease and cancer; and viral infections comprising HIV/AIDS. The company was formerly known as TNI BioTech, Inc. and changed its name to Immune Therapeutics, Inc. in December 2014. Immune Therapeutics, Inc. is headquartered in Orlando, Florida.

Phio Pharmaceuticals Company Profile

Phio Pharmaceuticals Corp., a biotechnology company, focuses on discovering and developing immuno-oncology therapeutics to treat cancer. The company's lead product candidate is RXI-109, an sd-rxRNA that reduces the expression of connective tissue growth factor, a critical regulator of several biological pathways involved in fibrosis, including scar formation in the skin and eye. The company also develops Samcyprone, a topical formulation of the small molecule diphenylcyclopropenone that is in a Phase IIa clinical trial for the clearance of common warts; RXI-231, an sd-rxRNA compound targeting tyrosinase, as a cosmetic ingredient that may enhance the appearance of uneven skin tone and pigmentation; and RXI-185, an sd-rxRNA compound targeting collagenase, as a cosmetic ingredient that may improve the appearance of wrinkles or skin laxity. In addition, it develops RXI-109, a Phase I/II clinical trial that reduces the progression of retinal scarring. The company has collaborations with the Center for Cancer Immune Therapy; Gustave Roussy; Medigene AG; PCI Biotech; and Karolinska Institutet. The company was formerly known as RXi Pharmaceuticals Corporation and changed its name to Phio Pharmaceuticals Corp. in November 2018. The company was incorporated in 2011 and is headquartered in Marlborough, Massachusetts.

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